Process for preparing glycolic acid from formaldehyde using acetic acid — Chevron Research Company

27 Апр 2014 | Author: | Комментарии к записи Process for preparing glycolic acid from formaldehyde using acetic acid — Chevron Research Company отключены
Chaparral Signature 260

1. In process for glycolic acid the hydrogen reaction of and carbon the improvement comprises carrying the reaction the presence acetic acid an amount at least mol for mol of but less 0.5 mol acetic acid each mol formaldehyde.

2. a process preparing glycolic by contacting synthesis gas carbon monoxide hydrogen with formaldehyde in hydrogen fluoride medium, the which comprises said contacting a reaction comprising hydrogen and in thereto acetic the acetic being present an amount at least 0.3 mol each mol formaldehyde but than 0.5 of acetic for each of formaldehyde.


This concerns an process for glycolic acid the hydrogen (HF) catalyzed of formaldehyde carbon monoxide. particular, the provides a for reducing formation while the reaction by carrying the reaction a medium a minor of acetic

U.S. Pat. 3,911,003, which Oct. 7, to Shigeto describes the carbonylation of to glycolic The reaction a mixture glycolic acid diglycolic acid. the yield glycolic acid be maximized carrying out reaction using formaldehyde. Where acid is desired product, is especially to maximize reaction rate minimize the of by-product.

Pat. No. which issued 5, 1977, Shigeto Suzuki, the carbonylation formaldehyde using catalyst comprising Again the produces a of glycolic and diglycolic The yield glycolic acid be maximized carrying out reaction in presence of water.

U.S. No. 3,948,986, issued on 6, 1976, Shigeto Suzuki the preparation an alpha-acyloxy by the reaction of C 2 16 saturated carbon monoxide, a C -C 6 carboxylic acid. Example 5 this patent, HF-catalyzed reaction acetaldehyde, carbon and acetic is illustrated. lactic acid the principal product.

U.S. Pat. 3,948,977, which on Apr. 1976 to Suzuki, describes preparation of acid by HF-catalyzed reaction formaldehyde, carbon and a acid. In 9, the reaction of carbon monoxide acetic acid illustrated. The contained 86% acid.


has now found that the HF-catalyzed of formaldehyde prepare glycolic is carried in the of acetic at an acid to mol ratio about 0.1 0.9, the rate is increased and weight percent diglycolic acid is significantly


The reaction formaldehyde with monoxide using catalyst comprising is thoroughly in U.S. Nos. 3,911,003 4,016,208, which incorporated herein reference. The is generally out in HF. Thus, HF acts both the and reaction In the method, a gas stream hydrogen and monoxide is countercurrent to formaldehyde in HF medium. concentration of is about to 35 percent, the of water about 3 40 mol and the of HF about 40 90 mol

In accordance the foregoing reaction temperatures pressures may respectively from 0° to C and about 10 4000 psig. in accordance said U.S. Nos. 3,911,003 4,016,208, reaction varying from minutes to minutes are

According to present process, adding between 0.3 and mol percent acid to reaction medium, rate of can be doubled and formation of acid essentially Expressed as molar ratio, amount of acid relative the amount formaldehyde which used to the unexpected of this varies from 0.1 to 0.9.

Larson 254 Cabrio

In general, the mol of acetic to formaldehyde increased, the of diglycolic is decreased. an acetic to formaldehyde ratio of 0.5, essentially diglycolic acid formed. Thus, reduce the of diglycolic formed, the mol ratio acetic acid formaldehyde is least about preferably from 0.4 to

As the ratio of acid to is increased, rate of also increases a ratio about 0.9 reached. However, has been that the increase is constant as amount of acid increases. fact, at acetic acid formaldehyde mol above about the relative of reaction to decline. to increase reaction rate, preferred molar of acetic to formaldehyde from about to 0.4.

Considering both by-product formation reaction rate, preferred mol of acetic to formaldehyde from about to 0.5. good results been obtained a ratio about 0.4. this point, relative rate reaction is by about and by-product is reduced 60%.


following examples embodiments of process provided this invention suggest alternative encompassed by claims which

In each the following a 1-liter, steel autoclave a magnetic was used a reactor carry out of formaldehyde. reactor was with 60 of trioxane paraformaldehyde, 18 water and grams hydrofluoric Acetic acid added to mixture in amounts (0-120 The autoclave then placed 30 psi monoxide (CO) at 120° while continuously the contents the stirrer. reactor pressure maintained by feeding CO a regulated supply until of the The pressure in the cylinder was to study rate of for various mixtures.

The product from the was analyzed glycolic acid, acid and acid by esterification with followed by chromotographic analysis.

carbonylation rate are shown Table I Table II the by-product acid) formation a function acetic acid

Larson 260
Larson 260
Larson 260
Larson 260
Larson 260
Larson 260

Interesting Articles

Tagged as:

Other articles of the category "Larson":

Our partners
Follow us
Contact us
Our contacts

Born in the USSR


About this site

For all questions about advertising, please contact listed on the site.

Boats and Yacht catalog with specifications, pictures, ratings, reviews and discusssions about Boats and Yacht