Phytosterols and phytostanols, new assessments on their beneficial effects | Italian Food Materials and Machinery

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Ferretti 2011

Phytosterols and new assessments their beneficial

The fortification foods with and phytostanols of considerable for food wishing to their products consumers who have slightly moderately high levels or want to this problem.

and phytostanols lipid molecules present in plant kingdom. main source which they extracted is as a of fact substances represent important by-product wood processing get cellulose; can be extracted from vegetable oils. have cholesterol-lowering i.e. they able to the absorption cholesterol (due structural analogy the same), with regular of appropriate in a but significant of cholesterol levels. Several studies have that with intake of least 1-3 of these (excess seems not make effectiveness and therefore not you get decrease in blood levels. decrease, seemingly is enough theory to a reduction ¼ cardiovascular already within few years. levels of in the are associated a higher of cardiovascular such as coronary diseases, ischemia, etc. this reason fortification of with these is of interest for companies wishing extend their to middle-aged (especially men), already have or moderately cholesterol levels who want prevent this without undergoing restrictive diets. the characteristics these groups substances, phytosterols, and their are steroid whose function to contribute the fluidity permeability of cell membranes. main structural between the groups lies the fact phytosterols have unsaturation (that a double bond) than (Figure 1). efficacy and at

this time are no conclusions about group of is better the other. molecules in group are but the abundant in are ß-sitosterol, and stigmasterol the first and sitostanol campestanol for latter. Thanks their structural with cholesterol, is very although it only of source (Figure phytosterols and are able prevent intestinal Lipids in and human are chiefly cholesterol esters, and phospholipids. lipids are in blood, need to transported in special way the cells, means of molecules: lipoproteins, which there several subtypes, LDL (low lipoproteins) and (high density Excess of in blood or hypertriglyceridemia), abnormalities in metabolism, or the ratio LDL and (in particular of LDL deficiency of lead to conditions that collectively referred as Dyslipidemia
which are due to disease. The of patients Dyslipidemia has over the 15 years the United according to Institute of of the States, and situation is much better Europe.

Figure 1. of cholesterol some phytosterols. are devoid the double between C5-C6. G. Garcìa-Llatas M.T. Rodrìguez-Estrada.

For these phytosterols and have been successfully to foods for 15 years, an always market due consumers’ awareness health and Among the fortified with or phytostanols successfully on market since end of 90s there mainly dairy such as (often simultaneously by reduced content) milk, and fermented cheeses, but products like salad dressings, cereal bars, cereals, fruit and other meat products bakery products example croissants muffins). It that to better phytosterols phytostanols bio-availability, is important them to in soluble therefore their in liquid semi-liquid foods the most   modality. amount of in the doesn’t seem be discriminating. the safe of these given the quantities (several per day) to achieve beneficial effect, are numerous that confirm harmlessness of and phytostanols, it should noted that there are long-term studies. negative effects be malabsorption beneficial lipids, as carotenes well as and phytostanols products, potentially The United FDA (Food Drug Administration) classified them the lowest category that GRAS (Generally as Safe). in Europe, use has approved and allowed to their addition foods with claims (according EC regulations

and 432/2012) to the of cholesterol which is important for companies interested launching this of product the market. the recent adopted on 26th, 2012 EFSA (European Safety Authority) effectiveness of substances is again.

“Response to on the Opinion on substantiation of health claim to 3 plant stanols plant stanol and lowering LDL-cholesterol and risk of heart disease to Article of Regulation No 1924/2006”. Report of Supporting Pubblications

T. Bacchetti S. Masciangelo V. Bicchiega E. Bertoli G. Ferretti 2011. Phytosterols, and their from natural functional foods Mediterranean Journal Nutrition and 4(3):165-172

Ferretti 2011

G. M.T. Rodrìguez-Estrada 2011. Current new insights phytosterol oxides plant sterol-enriched – Review. and Physics Lipids, 164:607:624

Majeed, L. . 2011. to the of the – Phytonutrients nutritional interventions support cardiovascular and wellness”. Corporation white

K. Weiner. Configuring users cholesterol lowering A review biomedical discourse. Science and 71(9):1541-1547

N. Jong, M.M. M.C. Ockè, Verhagen. 2008. general postlaunch framework for foods tested the phytosterol/-stanol Trends in Science and 19:535-545

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